Identification of GPR83 as the receptor for the neuroendocrine peptide PEN-Reference-Cited by-同舟云学术

Identification of GPR83 as the receptor for the neuroendocrine peptide PEN

Published:2016-04-26 Issue:425 Volume:9 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Gomes Ivone¹,Bobeck Erin N.¹,Margolis Elyssa B.²,Gupta Achla¹,Sierra Salvador¹,Fakira Amanda K.¹,Fujita Wakako¹,Müller Timo D.³⁴,Müller Anne⁵,Tschöp Matthias H.³⁴,Kleinau Gunnar⁵,Fricker Lloyd D.⁶,Devi Lakshmi A.¹⁷

Affiliation:

1. Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

2. Department of Neurology, University of California, San Francisco, San Francisco, CA 94158, USA.

3. Institute for Diabetes and Obesity, Helmholtz Diabetes Center, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany.

4. Division of Metabolic Diseases, Department of Medicine, Technische Universität München, 80333 Munich, Germany.

5. Institut für Experimentelle Pädiatrische Endokrinologie, Charité-Universitätsmedizin, 13125 Berlin, Germany.

6. Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

7. Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

Abstract

Functional coupling occurs between PEN-GPR83 and bigLEN-GPR171, ligand-receptor pairs implicated in feeding.

Funder

NIH

Alfonso Martin Escudero Foundation

Deutsche Forschungsgemeinschaft

Else Kroner-Fresenius-Stiftung (EKFS)

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

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