Autocrine Purinergic Receptor Signaling Is Essential for Macrophage Chemotaxis-Reference-Cited by-同舟云学术

Autocrine Purinergic Receptor Signaling Is Essential for Macrophage Chemotaxis

Published:2010-07-27 Issue:132 Volume:3 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Kronlage Moritz¹,Song Jian²,Sorokin Lydia²,Isfort Katrin¹,Schwerdtle Tanja³,Leipziger Jens⁴,Robaye Bernard⁵,Conley Pamela B.⁶,Kim Hee-Cheol⁷,Sargin Sarah¹,Schön Peter⁸,Schwab Albrecht¹,Hanley Peter J.¹

Affiliation:

1. Institut für Physiologie II, Wilhems-Universität Münster, 48149 Münster, Germany.

2. Institut für Physiologische Chemie und Pathobiochemie, Wilhems-Universität Münster, 48149 Münster, Germany.

3. Institut für Lebensmittelchemie, Wilhems-Universität Münster, 48149 Münster, Germany.

4. Institute of Physiology and Biophysics, Aarhus University, 8000 Aarhus, Denmark.

5. Institute of Interdisciplinary Research, Institute of Biology and Molecular Medicine, Université Libre de Bruxelles, 6041 Gosselies, Belgium.

6. Portola Pharmaceuticals, South San Francisco, CA 94080, USA.

7. Angewandte Biophysikalische Chemie, Philipps-Universität Marburg, 35032 Marburg, Germany.

8. Faculty of Science and Technology, Materials Science and Technology of Polymers, 7500 AE Enschede, the Netherlands.

Abstract

Amplification of outside-in chemotactic signaling by inside-out purinergic signaling drives macrophage migration.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference52 articles.

1. Cell Migration: Integrating Signals from Front to Back

2. Interstitial leukocyte migration and immune function

3. PIP3-Independent Activation of TorC2 and PKB at the Cell's Leading Edge Mediates Chemotaxis

4. Central Role for G Protein-Coupled Phosphoinositide 3-Kinase γ in Inflammation

5. Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration

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