Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice-Reference-Cited by-同舟云学术

Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice

Published:2015-05-05 Issue:375 Volume:8 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Morikawa Yuka¹,Zhang Min²³,Heallen Todd¹,Leach John²,Tao Ge²,Xiao Yang¹³,Bai Yan²³,Li Wei⁴,Willerson James T.¹,Martin James F.¹²⁵⁶

Affiliation:

1. Texas Heart Institute, Houston, TX 77030, USA.

2. Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX 77030, USA.

3. Institute of Biosciences and Technology, Texas A&M Health Science Center, Houston, TX 77030, USA.

4. Division of Biostatistics, Dan L. Duncan Cancer Center, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.

5. Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA.

6. Cardiovascular Research Institute, Baylor College of Medicine, Houston, TX 77030, USA.

Abstract

Inhibiting the Hippo pathway could promote heart regeneration by encouraging heart cells to move into injured areas.

Funder

Cancer Prevention and Research Institute of Texas (CPRIT)

Vivian L. Smith Foundation

American Heart Association

Baylor College of Medicine Intellectual and Developmental Disabilities Research Center (IDDRC)

NIH

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference51 articles.

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2. Evidence for Cardiomyocyte Renewal in Humans

3. Signaling effectors underlying pathologic growth and remodeling of the heart

4. Deaths: Final data for 2010;Murphy S. L.;Natl. Vital Stat. Rep.,2013

5. Transient Regenerative Potential of the Neonatal Mouse Heart

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