Inhibition of T cell activation and function by the adaptor protein CIN85-Reference-Cited by-同舟云学术

Inhibition of T cell activation and function by the adaptor protein CIN85

Published:2019-02-05 Issue:567 Volume:12 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Kong Mei Suen¹²^ORCID,Hashimoto-Tane Akiko¹^ORCID,Kawashima Yusuke³⁴^ORCID,Sakuma Machie¹,Yokosuka Tadashi¹^ORCID,Kometani Kohei⁵,Onishi Reiko¹^ORCID,Carpino Nick⁶,Ohara Osamu³⁴^ORCID,Kurosaki Tomohiro⁵⁷,Phua Kia Kien²^ORCID,Saito Takashi¹⁸^ORCID

Affiliation:

1. Laboratory for Cell Signaling, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045, Japan.

2. Institute for Research in Molecular Medicine, Main Campus, Universiti Sains Malaysia, 11800 Pulau Pinang, Malaysia.

3. Laboratory for Integrative Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045, Japan.

4. Department of Technology Development, Kazusa DNA Research Institute, Kisarazu, Chiba 292-0818, Japan.

5. Laboratory for Lymphocyte Differentiation, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045, Japan.

6. Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794-8434, USA.

7. Lymphocyte Differentiation, Immunology Frontier Research Center, Osaka University, Suita, Osaka 565-0871, Japan.

8. Cell Signaling, Immunology Frontier Research Center, Osaka University, Suita, Osaka 565-0871, Japan.

Abstract

The adaptor CIN85 inhibits T cell activation through its association with the phosphatase Sts-2 after TCR stimulation.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference57 articles.

1. An introduction to immunology and immunopathology

2. Cloning and Characterization of a Novel Adaptor Protein, CIN85, That Interacts with c-Cbl

3. Negative regulation of PI 3-kinase by Ruk, a novel adaptor protein

4. SETA is a multifunctional adapter protein with three SH3 domains that binds Grb2, Cbl, and the novel SB1 proteins

5. Assignment¹ of SH3KBP1 to human chromosome band Xp22.1→p21.3 by in situ hybridization

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