Impaired regulation of KCC2 phosphorylation leads to neuronal network dysfunction and neurodevelopmental pathology-Reference-Cited by-同舟云学术

Impaired regulation of KCC2 phosphorylation leads to neuronal network dysfunction and neurodevelopmental pathology

Published:2019-10-15 Issue:603 Volume:12 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Pisella Lucie I.¹^ORCID,Gaiarsa Jean-Luc¹^ORCID,Diabira Diabé¹^ORCID,Zhang Jinwei²^ORCID,Khalilov Ilgam¹³^ORCID,Duan JingJing⁴⁵^ORCID,Kahle Kristopher T.⁵^ORCID,Medina Igor¹^ORCID

Affiliation:

1. Aix-Marseille University, UMR 1249, INSERM (Institut National de la Santé et de la Recherche Médicale) Unité 1249, INMED (Institut de Neurobiologie de la Méditerranée), Marseille, France.

2. Institute of Biomedical and Clinical Sciences, College of Medicine and Health, University of Exeter Medical School, Hatherly Laboratories, Exeter EX4 4PS, UK.

3. Laboratory of Neurobiology, Kazan Federal University, Kazan 420008, Russia.

4. Department of Neurobiology, Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA 02115, USA.

5. Departments of Neurosurgery, Pediatrics, and Cellular and Molecular Physiology and Centers for Mendelian Genomics, Yale School of Medicine, New Haven, CT 06510, USA.

Abstract

Heterozygous knockin mice reveal role of the neuronal channel KCC2 in social and cognitive development.

Funder

NIH Blueprint for Neuroscience Research

Simons Foundation

March of Dimes Foundation

French Foundation of Epilepsy Research

French Ministry of Education

Ministry of Education and Research of Russian Federation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

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