Mechanosensitive ATP Release Maintains Proper Mucus Hydration of Airways-Reference-Cited by-同舟云学术

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Mechanosensitive ATP Release Maintains Proper Mucus Hydration of Airways

Published:2013-06-11 Issue:279 Volume:6 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Button Brian¹²,Okada Seiko F.¹,Frederick Charles Brandon²,Thelin William R.³,Boucher Richard C.¹

Affiliation:

1. Cystic Fibrosis Research and Treatment Center, University of North Carolina, Chapel Hill, NC 27599–7248, USA.

2. Department of Biomedical Engineering, University of North Carolina, Chapel Hill, NC 27599–7575, USA.

3. Parion Sciences, Durham, NC 27713, USA.

Abstract

Airway epithelial cells use purinergic signaling to optimize fluid secretion and mucus clearance.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference53 articles.

1. Effective Mucus Clearance Is Essential for Respiratory Health

2. Regulation of airway mucosal hydration

3. Altered O-glycosylation and sulfation of airway mucins associated with cystic fibrosis

4. CFTR, Mucins, and Mucus Obstruction in Cystic Fibrosis

5. Role of epithelial HCO3− transport in mucin secretion: lessons from cystic fibrosis

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