Potentiating antibiotics in drug-resistant clinical isolates via stimuli-activated superoxide generation-Reference-Cited by-同舟云学术

Potentiating antibiotics in drug-resistant clinical isolates via stimuli-activated superoxide generation

Published:2017-10-06 Issue:10 Volume:3 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Courtney Colleen M.¹^ORCID,Goodman Samuel M.¹²^ORCID,Nagy Toni A.³^ORCID,Levy Max¹²^ORCID,Bhusal Pallavi¹^ORCID,Madinger Nancy E.⁴^ORCID,Detweiler Corrella S.³^ORCID,Nagpal Prashant¹²⁵⁶,Chatterjee Anushree¹⁵^ORCID

Affiliation:

1. Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO 80303, USA.

2. Renewable and Sustainable Energy Institute, University of Colorado Boulder, Boulder, CO 80303, USA.

3. Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, CO 80309, USA.

4. Division of Infectious Diseases, University of Colorado Denver, Aurora, CO 80045, USA.

5. BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303, USA.

6. Materials Science and Engineering, University of Colorado Boulder, Boulder, CO 80303, USA.

Abstract

Engineered nanoparticle for controlled superoxide flux potentiates antibiotics in MDR clinical isolates.

Funder

Foundation for the National Institutes of Health

Division of Chemical, Bioengineering, Environmental, and Transport Systems

Defense Advanced Research Projects Agency

W.M. Keck Foundation

NSF Grant Fellowship

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference41 articles.

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2. U.S. Center for Disease Control and Prevention Antibiotic resistance threats in the United States 2013 (2013); www.cdc.gov/drugresistance/pdf/ar-threats-2013-508.pdf.

3. E. Tacconelli N. Magrini Global priority list of antibiotic-resistant bacteria to guide research discovery and development of new antibiotics (2017).

4. Eradication of bacterial persisters with antibiotic-generated hydroxyl radicals

5. Gyrase inhibitors induce an oxidative damage cellular death pathway in Escherichia coli;Dwyer D. J.;Mol. Syst. Biol.,2007

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