3D imaging of optically cleared tissue using a simplified CLARITY method and on-chip microscopy-Reference-Cited by-同舟云学术

3D imaging of optically cleared tissue using a simplified CLARITY method and on-chip microscopy

Published:2017-08-04 Issue:8 Volume:3 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Zhang Yibo¹²³,Shin Yoonjung²⁴,Sung Kevin²⁴,Yang Sam¹,Chen Harrison²,Wang Hongda¹²³,Teng Da⁵,Rivenson Yair¹²³,Kulkarni Rajan P.²³⁴⁶,Ozcan Aydogan¹²³⁷

Affiliation:

1. Electrical Engineering Department, University of California, Los Angeles, Los Angeles, CA 90095, USA.

2. Bioengineering Department, University of California, Los Angeles, Los Angeles, CA 90095, USA.

3. California NanoSystems Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA.

4. Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095 USA.

5. Computer Science Department, University of California, Los Angeles, Los Angeles, CA 90095, USA.

6. Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA.

7. Department of Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.

Abstract

Using lens-free holographic microscopy, we demonstrated 3D imaging in optically cleared tissue over a thickness of 0.2 mm.

Funder

National Science Foundation

Office of Naval Research

Howard Hughes Medical Institute

Army Research Office

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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