Co-infections determine patterns of mortality in a population exposed to parasite infection

Author:

Woolhouse Mark E. J.1,Thumbi Samuel M.12,Jennings Amy34,Chase-Topping Margo1,Callaby Rebecca15,Kiara Henry6,Oosthuizen Marinda C.7,Mbole-Kariuki Mary N.68,Conradie Ilana7,Handel Ian G.34,Poole E. Jane6,Njiiri Evalyne6,Collins Nicola E.7,Murray Gemma1,Tapio Miika9,Auguet Olga Tosas1,Weir Willie10,Morrison W. Ivan34,Kruuk Loeske E. B.111,Bronsvoort B. Mark de C.34,Hanotte Olivier8,Coetzer Koos7,Toye Philip G.6

Affiliation:

1. Centre for Immunity, Infection and Evolution, University of Edinburgh, Ashworth Laboratories, Kings Buildings, West Mains Road, Edinburgh EH9 3JT, UK.

2. Paul G. Allen School for Global Animal Health, Washington State University, Pullman, WA 99164–7090, USA.

3. Royal (Dick) School of Veterinary Studies, University of Edinburgh, The Roslin Building, Easter Bush, Midlothian EH25 9RG, UK.

4. The Roslin Institute, University of Edinburgh, The Roslin Building, Easter Bush, Midlothian EH25 9RG, UK.

5. The James Hutton Institute, Craigiebuckler, Aberdeen AB15 8QH, UK.

6. International Livestock Research Institute, P.O. Box 30709, Nairobi 00100, Kenya.

7. Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa.

8. School of Life Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UK.

9. Natural Resources Institute Finland (Luke), Green technology, FI-31600 Jokioinen, Finland.

10. Henry Wellcome Building, Institute of Biodiversity, Animal Health and Comparative Medicine, Garscube Campus, College of Medical, Veterinary and Life Sciences, University of Glasgow, Bearsden Road, Glasgow G61 1QH, UK.

11. Division of Evolution, Ecology and Genetics, Research School of Biology, The Australian National University, Canberra, Australian Capital Territory 0200, Australia.

Abstract

Highly protective effect of co-infections on mortality due to East Coast fever and consequences for disease epidemiology and control.

Funder

Wellcome Trust

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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