Secreted pectin monooxygenases drive plant infection by pathogenic oomycetes-Reference-Cited by-同舟云学术

Secreted pectin monooxygenases drive plant infection by pathogenic oomycetes

Published:2021-08-13 Issue:6556 Volume:373 Page:774-779
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Sabbadin Federico¹^ORCID,Urresti Saioa²^ORCID,Henrissat Bernard³⁴⁵^ORCID,Avrova Anna O.⁶^ORCID,Welsh Lydia R. J.⁶^ORCID,Lindley Peter J.²^ORCID,Csukai Michael⁷^ORCID,Squires Julie N.⁶^ORCID,Walton Paul H.²^ORCID,Davies Gideon J.²^ORCID,Bruce Neil C.¹^ORCID,Whisson Stephen C.⁶^ORCID,McQueen-Mason Simon J.¹^ORCID

Affiliation:

1. Centre for Novel Agricultural Products, Department of Biology, University of York, York YO10 5DD, UK.

2. Department of Chemistry, University of York, York YO10 5DD, UK.

3. Architecture et Fonction des Macromolécules Biologiques (AFMB), UMR 7257 CNRS, Université Aix-Marseille, 163 Avenue de Luminy, 13288 Marseille, France.

4. INRA, USC 1408 AFMB, 13288 Marseille, France.

5. Department of Biological Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.

6. Cell and Molecular Sciences, James Hutton Institute, Invergowrie, Dundee DD2 5DA, UK.

7. Syngenta, Jealott’s Hill International Research Centre, Bracknell, Berkshire RG42 6EY, UK.

Abstract

Potato pectin falls to Phytophthora Phytophthora infestans is a plant oomycete pathogen that drove the potato famines of the 1800s and continues to afflict potato fields today. The polysaccharide pectin makes up about a third of the cell wall in potatoes. Sabbadin et al . identified a family of lytic polysaccharide monooxygenases (LMPOs) that cleave pectin and are upregulated in P. infestans during infection. Silencing the relevant LMPO gene successfully inhibited P. infestans infections. These findings open doors for disease intervention targets and for biotech applications. —PJH

Funder

Rural and Environment Science and Analytical Services Division

Engineering and Physical Sciences Research Council

Biotechnology and Biological Sciences Research Council

Syngenta International

Syngenta

Scottish Government Rural and Environment Science and Analytical Services Division

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference58 articles.