Chromosome Segregation Errors as a Cause of DNA Damage and Structural Chromosome Aberrations-Reference-Cited by-同舟云学术

Chromosome Segregation Errors as a Cause of DNA Damage and Structural Chromosome Aberrations

Published:2011-09-30 Issue:6051 Volume:333 Page:1895-1898
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Janssen Aniek¹,van der Burg Marja²,Szuhai Karoly²,Kops Geert J. P. L.³,Medema René H.¹

Affiliation:

1. Department of Medical Oncology and Cancer Genomics Center, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG, Utrecht, Netherlands.

2. Department of Molecular Cell Biology, Leiden University Medical Center, Einthovenweg 20, 2300RC Leiden, Netherlands.

3. Department of Molecular Cancer Research and Cancer Genomics Center, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG, Utrecht, Netherlands.

Abstract

Altering whole-chromosome number can directly increase chromosome structural damage in cancer cells.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference28 articles.

1. Genetic instability in colorectal cancers

2. Whole chromosome instability and cancer: a complex relationship

3. Examining the link between chromosomal instability and aneuploidy in human cells

4. DNA Double Strand Breaks and Chromosomal Aberrations

5. S. L. Thompson D. A. Compton Chromosome Res. 19 433 (2010).

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