The impact of population-wide rapid antigen testing on SARS-CoV-2 prevalence in Slovakia-Reference-Cited by-同舟云学术

The impact of population-wide rapid antigen testing on SARS-CoV-2 prevalence in Slovakia

Published:2021-05-07 Issue:6542 Volume:372 Page:635-641
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Pavelka Martin¹²³^ORCID,Van-Zandvoort Kevin⁴⁵^ORCID,Abbott Sam⁴⁵^ORCID,Sherratt Katharine⁴⁵^ORCID,Majdan Marek⁶^ORCID,Jarčuška Pavol⁷,Krajčí Marek¹,Flasche Stefan⁴⁵^ORCID,Funk Sebastian⁴⁵^ORCID, ,

Affiliation:

1. Slovak Ministry of Health, Bratislava, Slovakia.

2. Inštitút Zdravotných Analýz (Institute of Health Analyses), Bratislava, Slovakia.

3. Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK.

4. Department for Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.

5. Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene and Tropical Medicine, London, UK.

6. Institute for Global Health and Epidemiology, Faculty of Health Sciences and Social Work, Trnava University, Trnava, Slovakia.

7. Faculty of Medicine, Pavol Jozef Šafárik University, Košice, Slovakia.

Abstract

The Slovakian test case Toward the end of 2020, Slovakia decided that it would test and then isolate positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cases among its entire population of ∼5.5 million, and more than 50,000 positive cases were found during a rapid antigen testing campaign. Pavelka et al. analyzed the data and found that in 41 counties before and after the two rounds of testing, infection prevalence declined by about 80% (see the Perspective by García-Fiñana and Buchan). They also used the data to test a microsimulation model for one county. Quarantine of the whole household after a positive test was essential to achieving a large reduction in prevalence. Since Autumn 2020, transmission in Slovakia has rebounded, despite other interventions, because high-intensity testing was not sustainable. Science , this issue p. 635 ; see also p. 571

Funder

Wellcome

ir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society

Elrha’s Research for Health in Humanitarian Crises

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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