Generation of Intestinal T Cells from Progenitors Residing in Gut Cryptopatches-Reference-Cited by-同舟云学术

Generation of Intestinal T Cells from Progenitors Residing in Gut Cryptopatches

Published:1998-04-10 Issue:5361 Volume:280 Page:275-278
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Saito Hisashi¹²³⁴⁵,Kanamori Yutaka¹²³⁴⁵,Takemori Toshitada¹²³⁴⁵,Nariuchi Hideo¹²³⁴⁵,Kubota Eiro¹²³⁴⁵,Takahashi-Iwanaga Hiromi¹²³⁴⁵,Iwanaga Toshihiko¹²³⁴⁵,Ishikawa Hiromichi¹²³⁴⁵

Affiliation:

1. H. Saito, Y. Kanamori, H. Ishikawa, Department of Microbiology, Keio University School of Medicine, Tokyo 160, Japan.

2. T. Takemori, Department of Immunology, National Institute of Infectious Diseases, Tokyo 162, Japan.

3. H. Nariuchi, Department of Allergology, Institute of Medical Science, University of Tokyo, Tokyo 108, Japan.

4. E. Kubota, Second Department of Oral and Maxillofacial Surgery, Kanagawa Dental College, Kanagawa 238, Japan.

5. H. Takahashi-Iwanaga, Department of Anatomy, School of Medicine, Hokkaido University, Sapporo 060, Japan.

Abstract

Cryptopatches (CPs) are part of the murine intestinal immune compartment. Cells isolated from CPs of the small intestine that were c-kit positive (c-kit + ) but lineage markers negative (Lin − ) gave rise to T cell receptor (TCR) αβ and TCR γδ intestinal intraepithelial T cells after in vivo transfer or tissue engraftment into severe combined immunodeficient mice. In contrast, cells from Peyer's patches and mesenteric lymph nodes, which belong in the same intestinal immune compartment but lack c-kit + Lin − cells, failed to do so. These findings and results of electron microscopic analysis provide evidence of a local intestinal T cell precursor that develops in the CPs.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference22 articles.

1. Zapata A., Bull. Inst. Pasteur81, 165 (1983); S. Tomonaga, T. Hirokame, K. Awaka, Zool. Mag.82, 215 (1973); L. D. Pasquier, in Evolution of the Immune System, Fundamental Immunology, W. E. Paul, Ed. (Raven, New York, 1993), pp. 199–233.

2. L. Lefrancois, L. Puddington, Immunol. Today 16, 16 (1995); J. R. Klein, J. Exp. Med. 184, 1203 (1996); G.-K. Sim, Adv. Immunol. 58, 297 (1995); Mowat A. M., Viney J. L., Immunol. Rev. 156, 145 (1997).

3. S. P. Balk, et al., Science 253, 1411 (1991); C. Van Kerckhove, et al., J. Exp. Med. 175, 57 (1992); Y. Chowers, W. Holtmeier, J. Harwood, E. Morzycka-Wroblewska, M. F. Kagnoff, ibid 180, 183 (1994); Regnault A., et al., Eur. J. Immunol. 26, 914 (1996).

4. M. Malissen, et al., EMBO J. 12, 4347 (1993); C. Liu et al., ibid., p. 4863; Park S. Y., et al., Eur. J. Immunol. 25, 2107 (1995).

5. N. Cerf-Bensussan, et al., Eur. J. Immunol. 17, 1279 (1987); Cepek K. L., et al., Nature 372, 190 (1994).

Cited by 266 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Ozone Environmental Pollution: Relationship between the Intestine and Neurodegenerative Diseases;Antioxidants;2023-06-22

2. Common and Exclusive Features of Intestinal Intraepithelial γδ T Cells and Other γδ T Cell Subsets;ImmunoHorizons;2022-07-01

3. Immunohistochemical characterisation of lymphoid subpopulations and CD34(+) cells in the lymphoid tissue of rabbit appendix;UKR J ECOL;2021

4. “Hierarchy” and “Holacracy”; A Paradigm of the Hematopoietic System;Cells;2019-09-24

5. Functional interactions between innate lymphoid cells and adaptive immunity;Nature Reviews Immunology;2019-07-26