Role of βγ Subunits of G Proteins in Targeting the β-Adrenergic Receptor Kinase to Membrane-Bound Receptors-Reference-Cited by-同舟云学术

Role of βγ Subunits of G Proteins in Targeting the β-Adrenergic Receptor Kinase to Membrane-Bound Receptors

Published:1992-08-28 Issue:5074 Volume:257 Page:1264-1267
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Pitcher Julie A.¹,Inglese James¹,Higgins Joyce B.²,Arriza Jeffery L.¹,Casey Patrick J.²,Kim Chong³,Benovic Jeffery L.³,Kwatra Madan M.¹,Caron Marc G.¹,Lefkowitz Robert J.¹

Affiliation:

1. Howard Hughes Medical Research Institute, Department of Medicine, Duke University Medical Center, Durham, NC 27710.

2. Section of Cell Growth, Regulation, and Oncogenesis and Department of Biochemistry, Duke University Medical Center, Durham, NC 27710.

3. Department of Pharmacology, Jefferson Cancer Institute, Thomas Jefferson University, Philadelphia, PA 19107.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference42 articles.

1. Regulation of Adenylyl Cyclase-Coupled beta-Adrenergic Receptors

2. Mammalian .beta.2-adrenergic receptor: purification and characterization

3. BENOVIC, J.L., AGONIST-DEPENDENT PHOSPHORYLATION OF THE ALPHA-2-ADRENERGIC RECEPTOR BY THE BETA-ADRENERGIC-RECEPTOR KINASE, JOURNAL OF BIOLOGICAL CHEMISTRY 262: 17251 (1987).

4. Benovic, J. L., Nature 321:869 (1986).

5. Beta-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor.

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