IFITM proteins inhibit placental syncytiotrophoblast formation and promote fetal demise

Author:

Buchrieser Julian12ORCID,Degrelle Séverine A.345ORCID,Couderc Thérèse67ORCID,Nevers Quentin12ORCID,Disson Olivier67ORCID,Manet Caroline8ORCID,Donahue Daniel A.12ORCID,Porrot Françoise12ORCID,Hillion Kenzo-Hugo9ORCID,Perthame Emeline9ORCID,Arroyo Marlene V.1210ORCID,Souquere Sylvie11ORCID,Ruigrok Katinka12ORCID,Dupressoir Anne1314ORCID,Heidmann Thierry1314ORCID,Montagutelli Xavier8ORCID,Fournier Thierry34ORCID,Lecuit Marc6715ORCID,Schwartz Olivier1216ORCID

Affiliation:

1. Virus and Immunity Unit, Department of Virology, Institut Pasteur, Paris, France.

2. CNRS-UMR3569, Paris, France.

3. INSERM, UMR-S1139, Faculté de Pharmacie de Paris, Paris, France.

4. Université Paris Descartes, Sorbonne Paris Cité, Paris, France.

5. Inovarion, Paris, France.

6. Institut Pasteur, Biology of Infection Unit, Paris, France.

7. Institut National de la Santé et de la Recherche Médicale U1117, Paris, France.

8. Mouse Genetics Laboratory, Department of Genomes and Genetics, Institut Pasteur, Paris, France.

9. Institut Pasteur, Bioinformatics and Biostatistics Hub, C3BI, USR 3756 IP CNRS, Paris, France.

10. Department of Biochemistry and Molecular Biophysics and Department of Microbiology and Immunology, Howard Hughes Medical Institute, Columbia University, New York, NY 10032, USA.

11. Plateforme de Microscopie Electronique Cellulaire, UMS AMMICA, Gustave Roussy, Villejuif, France.

12. Institut Pasteur, Structural Virology Unit and CNRS UMR3569, Paris, France.

13. Unité Physiologie et Pathologie Moléculaires des Rétrovirus Endogènes et Infectieux, CNRS UMR 9196, Gustave Roussy, Villejuif, France.

14. UMR 9196, Université Paris-Sud, Orsay, France.

15. Paris Descartes University, Department of Infectious Diseases and Tropical Medicine, Necker-Enfants Malades University Hospital, APHP, Institut Imagine, Paris, France.

16. Vaccine Research Institute, Créteil, France.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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