Three-Dimensional Structure of an Angiotensin II-Fab Complex at 3 Å: Hormone Recognition by an Anti-Idiotypic Antibody

Author:

Garcia K. Christopher1,Ronco Pierre M.2,Verroust Pierre J.2,Brünger Axel T.3,Amzel L. Mario1

Affiliation:

1. Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 21205.

2. INSERM Unité 64, Hôpital Tenon, Paris 75790 Cedex 20, France.

3. Howard Hughes Medical Institute and Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference42 articles.

1. AUMELAS, A, STUDIES ON ANGIOTENSIN-II AND ANALOGS - IMPACT OF SUBSTITUTION IN POSITION-8 ON CONFORMATION AND ACTIVITY, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 82: 1881 (1985).

2. BRUNGER, A.T., EXTENSION OF MOLECULAR REPLACEMENT - A NEW SEARCH STRATEGY BASED ON PATTERSON CORRELATION REFINEMENT, ACTA CRYSTALLOGRAPHICA SECTION A 46: 46 (1990).

3. XPLOR Manual Version 2.1 1990

4. BUDISAVLJEVIC, M, ANGIOTENSIN-II (AII)-RELATED IDIOTYPIC NETWORK .2. HETEROGENEITY AND FINE SPECIFICITY OF AII INTERNAL IMAGES ANALYZED WITH MONOCLONAL-ANTIBODIES, JOURNAL OF IMMUNOLOGY 140: 3059 (1988).

5. BUDISAVLJEVIC, M, ANGIOTENSIN-II (AII)-RELATED IDIOTYPIC NETWORK .3. COMPARATIVE-ANALYSIS OF IDIOTOPES AND PARATOPES BORNE BY MONOCLONAL-ANTIBODIES RAISED AGAINST AII (AB1) AND ITS INTERNAL IMAGE (AB3), JOURNAL OF IMMUNOLOGY 145: 1440 (1990).

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