Red squirrels in the British Isles are infected with leprosy bacilli

Author:

Avanzi Charlotte1,del-Pozo Jorge2,Benjak Andrej1,Stevenson Karen3,Simpson Victor R.4,Busso Philippe1,McLuckie Joyce3,Loiseau Chloé1,Lawton Colin5,Schoening Janne6,Shaw Darren J.2,Piton Jérémie1,Vera-Cabrera Lucio7,Velarde-Felix Jesùs S.7,McDermott Fergal6,Gordon Stephen V.68910,Cole Stewart T.1,Meredith Anna L.2

Affiliation:

1. Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.

2. Royal (Dick) School of Veterinary Studies and Roslin Institute, University of Edinburgh, Easter Bush Campus, Roslin, Scotland, UK.

3. Moredun Research Institute, Pentlands Science Park, Bush Loan, Edinburgh, Scotland, UK.

4. Wildlife Veterinary Investigation Centre, Chacewater, Cornwall, UK.

5. School of Natural Sciences, Ryan Institute, National University of Ireland, Galway, Ireland.

6. UCD School of Veterinary Medicine, University College Dublin, Belfield, Dublin, Ireland.

7. Laboratorio Interdisciplinario de Investigación Dermatológica, Servicio de Dermatología, Hospital Universitario, Monterrey, N.L., Mexico.

8. UCD School of Medicine, University College Dublin, Belfield, Dublin, Ireland.

9. UCD School of Biomolecular and Biomedical Science, University College Dublin, Belfield, Dublin, Ireland.

10. UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland.

Abstract

British squirrels infected with leprosy With the exception of armadillos in the Americas, leprosy infections are considered almost exclusively restricted to humans. Avanzi et al. examined warty growths on the faces and extremities of red squirrels in the British Isles and found that two species of leprosy-causing organisms were to blame (see the Perspective by Stinear and Brosch). Mycobacterium leprae in the southern population of Brownsea Island squirrels originated from a medieval human strain. M. lepromatosis was found in red squirrels from elsewhere in the United Kingdom and Ireland. Human leprosy is proving hard to eradicate, despite available drugs. Perhaps other wildlife species are also reservoirs for this stubborn disease. Science , this issue p. 744 ; see also p. 702

Funder

Fondation Raoul Follereau

Swiss National Science Foundation

Scottish Government Rural and Environment Science and Analytical Services Division

Thomas O'Hanlon Memorial Award in Veterinary Medicine

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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