Biodegradable, Elastic Shape-Memory Polymers for Potential Biomedical Applications

Author:

Lendlein Andreas1,Langer Robert2

Affiliation:

1. mnemoScience GmbH, Pauwelsstraβe 19, D-52074 Aachen, and Institute for Technical and Macromolecular Chemistry, RWTH Aachen, Germany.

2. Department of Chemical Engineering, Massachusetts Institute of Technology, 45 Carleton Street, Cambridge, MA 02139, USA.

Abstract

The introduction of biodegradable implant materials as well as minimally invasive surgical procedures in medicine has substantially improved health care within the past few decades. This report describes a group of degradable thermoplastic polymers that are able to change their shape after an increase in temperature. Their shape-memory capability enables bulky implants to be placed in the body through small incisions or to perform complex mechanical deformations automatically. A smart degradable suture was created to illustrate the potential of these shape-memory thermoplastics in biomedical applications.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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