Crystal Structure of a Catalytic Antibody with a Serine Protease Active Site

Author:

Zhou G. Wayne1,Guo Jincan2,Huang Wei2,Fletterick Robert J.1,Scanlan Thomas S.2

Affiliation:

1. Department of Biochemistry and Biophysics and Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 941 43-0448, USA.

2. Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94143-0446, USA.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference39 articles.

1. ABRAHMSEN, L, ENGINEERING SUBTILISIN AND ITS SUBSTRATES FOR EFFICIENT LIGATION OF PEPTIDE-BONDS IN AQUEOUS-SOLUTION, BIOCHEMISTRY 30: 4151 (1991).

2. Enzyme Structure and Function 1976

3. BONE, R, STRUCTURAL PLASTICITY BROADENS THE SPECIFICITY OF AN ENGINEERED PROTEASE, NATURE 339: 191 (1989).

4. BRUNGER, A.T., 2.9 A-RESOLUTION STRUCTURE OF AN ANTI-DINITROPHENYL-SPIN-LABEL MONOCLONAL-ANTIBODY FAB FRAGMENT WITH BOUND HAPTEN, JOURNAL OF MOLECULAR BIOLOGY 221: 239 (1991).

5. X-PLOR Manual Version 3.1 1992

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