Dynamic DNA devices and assemblies formed by shape-complementary, non–base pairing 3D components-Reference-Cited by-同舟云学术

Dynamic DNA devices and assemblies formed by shape-complementary, non–base pairing 3D components

Published:2015-03-27 Issue:6229 Volume:347 Page:1446-1452
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Gerling Thomas¹,Wagenbauer Klaus F.¹,Neuner Andrea M.¹,Dietz Hendrik¹

Affiliation:

1. Physik Department, Walter Schottky Institute, Technische Universität München Am Coulombwall 4a, 85748 Garching near Munich, Germany

Abstract

Reconfigurable DNA structures DNA origami—nanostructures created by programming the assembly of single-stranded DNA through base pairing—can create intricate structures. However, such structures lack the flexible and reversible interactions more typical of biomolecular recognition. Gerling et al. created three-dimensional DNA nanostructures that assemble though nucleotide base-stacking interactions (see the Perspective by Shih). These structures cycled from open to closed states with changes in salt concentration or temperature. Science, this issue p. 1446 ; see also p. 1417

Funder

European Research Council

Deutsche Forschungsgemeinschaft

Hans L. Merkle Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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