A Unified Polymerase Mechanism for Nonhomologous DNA and RNA Polymerases

Author:

Steitz T. A.12,Smerdon S. J.1,Jäger J.1,Joyce C. M.1

Affiliation:

1. Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520-8114, USA

2. Department of Chemistry, Yale University, New Haven, CT 06520-8114, USA

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference26 articles.

1. ANDERSON, J, COCRYSTALS OF THE DNA-BINDING DOMAIN OF PHAGE-434 REPRESSOR AND A SYNTHETIC PHAGE 434 OPERATOR, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 81: 1307 (1984).

2. BEESE, L.S., STRUCTURAL BASIS FOR THE 3'-5' EXONUCLEASE ACTIVITY OF ESCHERICHIA-COLI DNA-POLYMERASE-I - A 2 METAL-ION MECHANISM, EMBO JOURNAL 10: 25 (1991).

3. Structure of DNA Polymerase I Klenow Fragment Bound to Duplex DNA

4. BEESE L.S. unpublished data.

5. DAVIES, J.F., 2.3-ANGSTROM CRYSTAL-STRUCTURE OF THE CATALYTIC DOMAIN OF DNA POLYMERASE-BETA, CELL 76: 1123 (1994).

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