1. Genetics Department and Research Institute, Hospital for Sick Children, and Departments of Medical Genetics and Medical Biophysics, University of Toronto, Toronto, Ontario, Canada, M5G 1X8.
2. Paediatric Research Unit, United Medical and Dental Schools of Guy's and St. Thomas's Hospitals, Guy's Hospital, London SE1 9RT, United Kingdom.
3. Section of Medical Genetics, University of Wales College of Medicine, Health Park, Cardiff CF4 4XN, United Kingdom.