Plant-produced biopharmaceuticals: A case of technical developments driving clinical deployment

Author:

Lomonossoff George P.1,D’Aoust Marc-André2

Affiliation:

1. Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.

2. Medicago, 1020 Route de l’Église, Bureau 600, Quebec City, Quebec G1V 3V9, Canada.

Funder

U.K. Biotechnological and Biological Sciences Research Council Institute Strategic Programme

John Innes Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference40 articles.

1. European Medicines Agency “Guidelines on the quality of biologically active substances produced by stable transgene expression in higher plants ” www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2009/09/WC500003154.pdf.

2. Production of antibodies in transgenic plants

3. Expression of hepatitis B surface antigen in transgenic plants.

4. Generation and Assembly of Secretory Antibodies in Plants

5. Oral Immunization with a Recombinant Bacterial Antigen Produced in Transgenic Plants

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