Mutations in Diphtheria Toxin Separate Binding from Entry and Amplify Immunotoxin Selectivity
Author:
Affiliation:
1. Department of Microbial Genetics, Cetus Corporation, Emeryville, CA 94608.
2. Surgical Neurology Branch, National Institute of Neurological and Communicative Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
Publisher
American Association for the Advancement of Science (AAAS)
Subject
Multidisciplinary
Reference40 articles.
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2. Chaudhary, V. K., Proceedings of the National Academy of Sciences of the United States of America 84: 4538 (1987).
3. COLLIER, R.J., DIPHTHERIA-TOXIN - MODE OF ACTION AND STRUCTURE, BACTERIOLOGICAL REVIEWS 39: 54 (1975).
4. COLOMBATTI, M, CLONED FRAGMENT OF DIPHTHERIA-TOXIN LINKED TO T-CELL-SPECIFIC ANTIBODY IDENTIFIES REGIONS OF B-CHAIN ACTIVE IN CELL ENTRY, JOURNAL OF BIOLOGICAL CHEMISTRY 261: 3030 (1986).
5. EIKLID, K, ENTRY OF LETHAL DOSES OF ABRIN, RICIN AND MODECCIN INTO THE CYTOSOL OF HELA-CELLS, EXPERIMENTAL CELL RESEARCH 126: 321 (1980).
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