Patterns of Genome Organization in Bacteria-Reference-Cited by-同舟云学术

Patterns of Genome Organization in Bacteria

Published:1998-03-20 Issue:5358 Volume:279 Page:1827-1827
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Freeman James M.¹,Plasterer Thomas N.²,Smith Temple F.³,Mohr Scott C.⁴

Affiliation:

1. Biomolecular Engineering Research Center, Boston University, Boston, MA 02215, USA

2. Department of Pharmacology, Boston University

3. Biomolecular Engineering Research Center, Boston University

4. Department of Chemistry, Boston University

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference28 articles.

1. The Complete Genome Sequence of Escherichia coli K-12

2. The complete genome sequence of the Gram-positive bacterium Bacillus subtilis

3. Lobry J. R., Mol. Biol. Evol. 13, 650 (1996);

4. ; Science 272 745 (1996); Biochimie 78 323 (1996).

5. Purine excess: χ (l) = Σ[δ A S + δ G S − δ T S − δ C S ] where S is the base present at the current sequence position (l) the sum is performed over the range 1 to l and δ X Y = 1 if X = Y; and 0 if X ≠ Y. Interchanging the A and T subscripts in this equation defines the keto excess. A DNA sequence can be uniquely described as a walk through a three-dimensional vector space defined by two orthogonal axes for the two types of base pair and a third perpendicular axis that repre- sents the sequence position (3) (scheme). An A in the sequence corresponds to movement in the positive x direction and a T to the opposite. G and C are mapped by analogous steps along the y axis and sequence position increases along z.

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