RNAi in C. elegans : Soaking in the Genome Sequence

Author:

Tabara Hiroaki1,Grishok Alla1,Mello Craig C.1

Affiliation:

1. The authors are at the Cancer Center, Department of Cell Biology, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference17 articles.

1. par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed

2. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

3. Wnt Signaling and an APC-Related Gene Specify Endoderm in Early C. elegans Embryos

4. Timmons L., Fire A., Naturein press.

5. Grishok A. Mello C. C. unpublished results. We do not know whether this long-term transmission which is always somewhat less penetrant than the interference observed in the first two generations involves the same or a secondary interference mechanism.

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