The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence-Reference-Cited by-同舟云学术

The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence

Published:2011-12-23 Issue:6063 Volume:334 Page:1727-1731
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

Alvarez Jorge Ivan¹,Dodelet-Devillers Aurore¹,Kebir Hania¹,Ifergan Igal¹,Fabre Pierre J.²,Terouz Simone¹,Sabbagh Mike¹,Wosik Karolina¹,Bourbonnière Lyne¹,Bernard Monique¹,van Horssen Jack³,de Vries Helga E.³,Charron Frédéric²,Prat Alexandre¹

Affiliation:

1. Neuroimmunology Unit, Center of Excellence in Neuromics, Centre de Recherche du Centre Hospitalier de l’Université de Montréal, Faculty of Medicine, Université de Montréal, Montréal, Quebec, H2L 4M1, Canada.

2. Laboratory of Molecular Biology of Neural Development, Institut de Recherches Cliniques de Montréal and Department of Medicine, Université de Montréal, Montréal, Quebec, H2W 1R7, Canada.

3. Department of Molecular Cell Biology and Immunology, VU Medical Center, 1007 MB Amsterdam, Netherlands.

Abstract

Hedgehog signaling is required for maintaining the integrity of the blood-brain barrier.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference43 articles.

1. Functions of lipid raft membrane microdomains at the blood–brain barrier

2. Astrocyte–endothelial interactions at the blood–brain barrier

3. Tight junctions of brain endothelium in vitro are enhanced by astroglia

4. Glial cell influence on the human blood-brain barrier

5. Astrocyte-mediated induction of tight junctions in brain capillary endothelium: an efficient in vitro model

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