Significant Species Differences in Intestinal Phosphate Absorption between Dogs, Rats, and Monkeys

Author:

ICHIDA Yasuhiro1,HOSOKAWA Naoto1,TAKEMOTO Ryushi2,KOIKE Takafumi2,NAKATOGAWA Tasuku2,HIRANUMA Mayumi2,ARAKAWA Hitoshi2,MIURA Yukihito2,AZABU Hiroko2,OHTOMO Shuichi1,HORIBA Naoshi1

Affiliation:

1. Research Division, Chugai Pharmaceutical Co., Ltd.

2. Chugai Research Institute for Medical Science, Inc.

Publisher

Center for Academic Publications Japan

Subject

Nutrition and Dietetics,Medicine (miscellaneous)

Reference30 articles.

1. 1) Murer H, Forster I, Hernando N, Lambert G, Traebert M, Biber J. 1999. Posttranscriptional regulation of the proximal tubule NaPi-II transporter in response to PTH and dietary P(i). Am J Physiol 277: F676-684.

2. 2) Segawa H, Kawakami E, Kaneko I, Kuwahata M, Ito M, Kusano K, Saito H, Fukushima N, Miyamoto K. 2003. Effect of hydrolysis-resistant FGF23-R179Q on dietary phosphate regulation of the renal type-II Na/Pi transporter. Pflugers Arch 446: 585-592.

3. 3) Larsson T, Nisbeth U, Ljunggren O, Juppner H, Jonsson KB. 2003. Circulating concentration of FGF-23 increases as renal function declines in patients with chronic kidney disease, but does not change in response to variation in phosphate intake in healthy volunteers. Kidney Int 64: 2272-2279.

4. 4) Voormolen N, Noordzij M, Grootendorst DC, Beetz I, Sijpkens YW, van Manen JG, Boeschoten EW, Huisman RM, Krediet RT, Dekker FW, PREPARE study group. 2007. High plasma phosphate as a risk factor for decline in renal function and mortality in pre-dialysis patients. Nephrol Dial Transplant 22: 2909-2916.

5. 5) Tentori F, Blayney MJ, Albert JM, Gillespie BW, Kerr PG, Bommer J, Young EW, Akizawa T, Akiba T, Pisoni RL, Robinson BM, Port FK. 2008. Mortality risk for dialysis patients with different levels of serum calcium, phosphorus, and PTH: the Dialysis Outcomes and Practice Patterns Study (DOPPS). Am J Kidney Dis 52: 519-530.

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