Nanosilver Application in Dental Cements

Author:

Magalhães Ana Paula Rodrigues1,Santos Laura Barbosa1,Lopes Lawrence Gonzaga1,Estrela Cyntia Rodrigues de Araújo2,Estrela Carlos2,Torres Érica Miranda1,Bakuzis Andris Figueiroa3,Cardoso Paula Carvalho1,Carrião Marcus Santos3

Affiliation:

1. Department of Prevention and Oral Rehabilitation, School of Dentistry, Federal University of Goiás, 74605220 Goiânia, GO, Brazil

2. Department of Oral Science, School of Dentistry, Federal University of Goiás, 74605220 Goiânia, GO, Brazil

3. Physics Institute, Federal University of Goiás, 74001970 Goiânia, GO, Brazil

Abstract

Streptococcus mutans is the microorganism mostly responsible for initiation of tooth decay and also for the progression of an established lesion. Silver has been used for its antibacterial properties for many years, in different forms: ionised and elementary forms, as silver zeolites or as nanoparticles. The purpose of this study was to evaluate the antibacterial activity of three dental cements modified by nanosilver. Three cements were used: Sealapex, RelyX ARC, and Vitrebond. The cements were incorporated with 0.05 mL of silver nanoparticles solution. Control groups were prepared without silver. Six Petri plates with BHI were inoculated with S. mutans using sterile swabs. Three cavities were made in each agar plate (total = 18) and filled with the manipulated cements. They were incubated at 37°C for 48 h, and the inhibition halos were measured. The paired t-Test was used for statistical analysis (P<0.05). No inhibition halos were obtained for Sealapex and Rely X, but Vitrebond showed bactericidal activity without silver and enhanced effect with silver incorporation.

Publisher

Hindawi Limited

Subject

Pharmacology (medical),Complementary and alternative medicine,Pharmaceutical Science

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