Regulation of GLUT4 and Insulin-Dependent Glucose Flux-Reference-Cited by-同舟云学术

Regulation of GLUT4 and Insulin-Dependent Glucose Flux

Published:2012-10-17 Issue: Volume:2012 Page:1-12
ISSN:2090-7907
Container-title:ISRN Molecular Biology
language:en
Short-container-title:ISRN Molecular Biology

Author:

Olson Ann Louise¹

Affiliation:

1. Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, P.O. Box 26901, BMSB 964, Oklahoma City, OK 73190, USA

Abstract

GLUT4 has long been known to be an insulin responsive glucose transporter. Regulation of GLUT4 has been a major focus of research on the cause and prevention of type 2 diabetes. Understanding how insulin signaling alters the intracellular trafficking of GLUT4 as well as understanding the fate of glucose transported into the cell by GLUT4 will be critically important for seeking solutions to the current rise in diabetes and metabolic disease.

Publisher

Hindawi Limited

Subject

General Medicine

Link

http://downloads.hindawi.com/archive/2012/856987.pdf

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