Case Report: Effect of hyaluronic acid-enriched medium in case of post-menopausal in vitro fertilisation pregnancy

Abstract

Hyaluronate-enriched medium has been gaining attention from researchers worldwide for its effectiveness in improving the success rate of embryo transfer following implantation in those patients who suffer from recurrent implantation failure. This article reports the case of a 49-year-old patient who was unable to get pregnant naturally, and with a history of three spontaneous abortions in her 20 years marriage period. The patient also had a history of four in vitro fertilisation (IVF) cycle failures before enrolling at Wardha Test Tube Baby Centre situated in Sawangi, India in August 2020. The patient had positive clinical pregnancy using conventional culture media devoid of hyaluronan instead of hyaluronan-enriched media. This case report enlightens the fact that embryo transfer may be unsuccessful using hyaluronan-enriched media in the case of post-menopausal patients.