Defining the burden of febrile illness in rural South and Southeast Asia: an open letter to announce the launch of the Rural Febrile Illness project

Author:

Chandna ArjunORCID,Chew RushengORCID,Shwe Nwe Htun Nan,Peto Thomas J.ORCID,Zhang Meiwen,Liverani Marco,Brummaier TobiasORCID,Phommasone Koukeo,Perrone CarloORCID,Pyae Phyo AungORCID,Sattabongkot JetsumonORCID,Roobsoong Wanlapa,Nguitragool WangORCID,Sen Aninda,Ibna Zaman SazidORCID,Sandar Zaw Aye,Batty ElizabethORCID,Waithira NaomiORCID,Abdad Mohammad YazidORCID,Blacksell Stuart D.,Bodhidatta Ladaporn,Callery James J.ORCID,Fagnark Watcharintorn,Huangsuranun Witchayoot,Islam Shayla,Lertcharoenchoke Sanchai,Lohavittayavikant Salisa,Mukaka Mavuto,Moul Vanna,Kumer Neogi AmitORCID,Nedsuwan Supalert,Pongvongsa Tiengkham,Ponsap Pimsiri,Richard-Greenblatt MelissaORCID,Schilling William H.K.ORCID,Thaipadungpanit JanjiraORCID,Tripura RupamORCID,Dondorp Arjen M.ORCID,Mayxay MayfongORCID,White Nicholas J.ORCID,Nosten FrançoisORCID,Smithuis FrankORCID,Ashley Elizabeth A.ORCID,Maude Richard J.ORCID,Day Nicholas P.J.ORCID,Lubell YoelORCID

Abstract

In rural areas of South and Southeast Asia malaria is declining but febrile illnesses still account for substantial morbidity and mortality. Village health workers (VHWs) are often the first point of contact with the formal health system, and for patients with febrile illnesses they can provide early diagnosis and treatment of malaria. However, for the majority of febrile patients, VHWs lack the training, support and resources to provide further care. Consequently, treatable bacterial illnesses are missed, antibiotics are overused and poorly targeted, and patient attendance wanes along with declining malaria. This Open Letter announces the start of a new initiative, the Rural Febrile Illness (RFI) project, the first in a series of projects to be implemented as part of the South and Southeast Asian Community-based Trials Network (SEACTN) research programme. This multi-country, multi-site project will run in Bangladesh, Cambodia, Lao PDR, Thailand, and Myanmar. It will define the epidemiological baseline of febrile illness in nine remote and underserved areas of Asia where malaria endemicity is declining and access to health services is limited. The RFI project aims to determine the incidence, causes and outcomes of febrile illness; understand the opportunities, barriers and appetite for adjustment of the role of VHWs to include management of non-malarial febrile illnesses; and establish a network of community healthcare providers and facilities capable of implementing interventions designed to triage, diagnose and treat patients presenting with febrile illnesses within these communities in the future.

Funder

Global Fund to Fight AIDS, Tuberculosis and Malaria

Wellcome Trust

Publisher

F1000 Research Ltd

Subject

General Biochemistry, Genetics and Molecular Biology,Medicine (miscellaneous)

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