Allium sativum and Group B Streptococcus: antimicrobial and synergistic activity-Reference-Cited by-同舟云学术

Allium sativum and Group B Streptococcus: antimicrobial and synergistic activity

Published:2024-03-12 Issue: Volume: Page:
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Author:

Lima Sônia Maria Rolim Rosa¹,Gamberini Maria Thereza¹,Rodrigues Domingos Sávio²,Junior Pedro Ismael da Silva³,Torres Kátia Andrea de Menezes¹

Affiliation:

1. Santa Casa de Sao Paulo School of Medical Sciences, São Paulo/SP, Brazil

2. Center for Biodiversity Conservation of the Research Institute (IPA), Secretariat of Infrastructure and the Environment (SIMA), São Paulo/SP, Brazil.

3. Laboratory for Applied Toxinology - Center of Toxins, Immune-Response and Cell Signaling – CeTICS/CEPID, Butantan Institute, São Paulo/SP, Brazil

Abstract

Abstract Objective The study aimed to evaluate the antimicrobial activity of the SP80 fraction (obtained from Allium sativum) and its synergism with the antibiotic against strains of GBS. Methods The broth microdilution and disk diffusion assays were used to determine the antimicrobial and synergistic activity of Sep-pak 80% (SP80) in combination with ampicillin and penicillin G, respectively. Results The results showed that the combination of SP80 and antibiotics respectively showed an additive effect. Conclusions The SP80 fraction has antimicrobial activity against GBS, and the association with the antibiotic has an additive effect.

Publisher

Research Square Platform LLC

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