Abstract
Objective: To analyze and compare the application and efficacy of side-to-side anastomosis and end-to-end anastomosis in NOSES operation for left colon cancer.
Methods: A retrospective analysis of 69 patients in our hospital from February 2018 to February 2022 who underwent natural orifice specimen extraction surgery (NOSES) for left colon tumors. The observation group was performed with side-to-side anastomosis (Overlap). For digestive tract reconstruction, the control group was anastomosed by end-to-end anastomosis; the intraoperative and postoperative conditions and complications were compared between the two groups.
Results: There was no significant difference in operation time and intraoperative blood loss between the two groups (P>0.05). However, the intraoperative anastomosis time in the observation group was significantly shorter than that in the control group (P<0.001). Additionally, there was no significant difference in the time of first exhaustion, defecation time, degree of patency of defecation, frequency of defecation, postoperative hospital stays and postoperative pain between the two groups (P>0.05). Furthermore, the overall incidence of postoperative complications did not show a significant difference (P>0.05).
Conclusions: In the NOSES surgery of left colon cancer, both side-to-side anastomosis (Overlap) and end-to-end anastomosis yield comparable radical outcomes., but the side-to-side anastomosis (Overlap) method is operationally simpler and has a shorter intraoperative anastomosis time. As such, this method is the preferred anastomosis method when NOSES for colorectal cancer is carried out in primary hospitals.
Trial registration number ChiCTR1900026104 (2019-09-21)