Post contrast three dimensional MP RAGE T1WI sequence compared to brain MRV (TOF study) in diagnosing brain sinus venous thrombosis

Abstract

Abstract Aim : To compare the accuracy of MRV TOF and post contrast MP-RAGE sequences in diagnosis of cerebral sinus venous thrombosis . Methods and materials : After all informed consents were obtained and upon ethical committee approval from the ethical committee in Joradanian Royal medical services in Amman we perform this study as a retrospective study done on 50 patients with cerebral sinus venous thrombosis with 50 pateints control group done at king Hussein medical center in Amman Jordan . The guidelines and regulations of studies conducted in Royal medical services were followed . 68 females and 32 males with age range between 19 and 52 years All patients underwent brain MRI for evaluation of cerebral sinus thrombosis , all studies were done on seimens skyra 3 tesla machine with standardized protocol including 2 D TOF MRV , axial T2WI , axial FLAIR , Axial T1 , SWI and diffusion weighted images along with 3D MP-RAGE post contrast . Images were reviewed by two well experienced neuroradiologists ( Maysoon and Qamar ) in separate sessions , each MRI sequence was reported separately without knowing patients name or clinical history . The results for T2 WI , SWI , MRV TOF and MP-RAGE post contrast were reported . We used a confidence level score to standardize the results Then the results were analyzed using simple statistical methods .