Associations Between Anemia and Dependence on Basic and Instrumental Activities of Daily Living in Older Women

Author:

Karismaz Abdulkadir1,Pasin Ozge2,Kara Osman3,Eren Rafet4,Smith Lee5,Doventas Alper6,Soysal Pinar7

Affiliation:

1. University of Health Sciences, Istanbul Training and Research Hospital

2. Bezmialem University Faculty of Medicine

3. Bahcesehir University Medical Park Goztepe Hospital

4. Istinye University

5. Anglia Ruskin University

6. Istanbul University-Cerrahpasa

7. Bezmialem Vakif University

Abstract

Abstract

Aim The aim of the present study was to examine the relationship between anemia and basic and instrumental activities of daily living in older female patients. Methods 540 older female outpatients were included. Anemia was defined as a hemoglobin below 12 g/dL. Patients' demographic characteristics, comorbidities, Geriatric Depression Scale, Mini Nutritional Assessment, and Mini-Mental State Examination (MMSE) were also recorded. Handgrip strength (HGS) was measured with a hand dynamometer to detect dynapenia. Basic Activities of Daily Living (BADL) and Instrumental Activities of Daily Living (IADL) questionnaires were used to evaluate functional capacity. Results The mean age of the participants was 77.42 ± 7.42. The prevalence of patients with anemia was 35%. A significant difference was observed between anemic and non-anemic groups in terms of age, presence of diabetes mellitus, hypertension, (DM) coronary artery disease (CAD), chronic kidney disease (CKD), malnutrition, dynapenia, and MMSE, BADL and IADL scores (p < 0.05). In multivariate analysis, after adjustment for age, DM, hypertension, CAD and CKD; there were significant associations between anemia and reduced BADL/IADL scores, dynapenia, falls, the risk of falls, MMSE, and malnutrition (p < 0.05). After adjusting for all confounding variables, deterioration in total BADL and IADL total scores were still more common among anemic older females than those without anemia (p < 0.05). Conclusion One out of every three older women presenting at outpatient clinic were anemic. Anemia was observed to be associated with dependence in both BADL and IADL measures. Therefore, the presence of anemia in elderly women should be routinely checked, and possible causes should be investigated and treated to improve their functional capacity.

Publisher

Springer Science and Business Media LLC

Reference46 articles.

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4. Anemia in the elderly: clinical implications and new therapeutic concepts;Stauder R;Haematologica,2014

5. Stauder R, Valent P, Theurl I. Anemia at older age: etiologies, clinical implications, and management. Blood. 2018; 1;131(5):505–514.

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