Synthesis of 2,9-dihydropyrano[2,3-b]-indoles via intramolecular Oxa-6π-electrocyclization reaction from synthesized 3-allylideneindolin-2-one intermediates

Author:

Varnakesh Parisa Abbasi1,Azizian Javad1ORCID

Affiliation:

1. Islamic Azad University Science and Research Branch

Abstract

Abstract intramolecular Oxa-6π-electrocyclization reaction are described for 3-allylideneindolin-2-one derivatives in the presence of easily prepared B(HSO4)3 catalyst and their conversion to 2,9-dihydropyrano[2,3-b]-indoles in up to 72% yield under mild condition. 3-allylideneindolin-2-one has been obtained from the reaction of isatin and 1,3-dichloropropene. comfortable synthetic conversions of the products readily lead to pharmacologically interesting numerous functional groups.

Publisher

Research Square Platform LLC

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