Abstract
Background
Aspergillus spp. are rare causes of surgical site infections (SSIs). Aspergillus section Nigri, commonly identified as Aspergillus niger through morphological findings, has been sparsely reported as a cause of abdominal SSIs.
Case presentation
An 86-year-old woman with a history of hypertension, chronic kidney disease, and atrial fibrillation who was taking 6 mg of prednisolone daily for rheumatoid arthritis was admitted to our hospital because of sudden abdominal pain. An open Hartmann operation was performed on the day of admission with a diagnosis of sigmoid colon perforation. A superficial abdominal SSI was observed. Aspergillus welwitschiae, which belongs to Aspergillus section Nigri, was identified through calmodulin gene analysis. The minimum inhibitory concentration (MIC) of voriconazole (VRCZ) was 2 mg/L. Surgical removal of the infected tissue and administration of VRCZ were effective in treating the infection.
Conclusions
Given the reported tolerance of azoles in Nigri section species, identification and drug susceptibility testing of these fungi are highly important.