Magnitude and Associated Factors of intraoperative hyperglycemia among orthopedics surgical patients. A cross-sectional study

Author:

Gebeyehu Geresu1,Leta Gutu2,shiferaw selamawit1

Affiliation:

1. Addis Ababa University

2. Wollega Universiry

Abstract

Abstract Background: Intraoperative hyperglycemia is a common problem among patients undergoing orthopedic surgery. Its incidence varies from country to country and not clearly studied in developing countries. Method:Multi-center cross-sectional study was conducted on eligible adult elective patients who underwent orthopedic surgical procedures. The participants were selected using a systematic random sampling technique. Data was collected on basic characteristics, medical and surgical history. On the arrival of patients to the OR, blood glucose was measured and recorded and repeated after administering anesthesia. The data was analyzed using descriptive statistics and bivariate and multivariate logistic regression. P<0.05 was considered as statistically significant. Results: Intraoperative hyperglycemia was observed in 20.4% of patients. Hypothermia (AOR:2.45;95% CI:0.97-6.27, p=0.05), infused dextrose iv fluids (AOR:2.94;95% CI:1.64-5.16, p=0.05) , blood transfusion (AOR:6.64;95% CI:2.92-15.08, p=0.00) and history of hypertension (AOR:2.19;95% CI:1.23-3.71, p=0.01) were factors identified to be associated with intraoperative hyperglycemia. Conclusions and recommendations This study showed the magnitude of intraoperative hyperglycemia was high. Anesthetists should identify all risk factors preoperatively and make appropriate adjustments for patient care. Hypertension should be optimized, refrain from routine administering of dextrose IV fluids, and unnecessary transfusions, as well as monitor patients’ body temperature.

Funder

Addis Ababa University

Publisher

Research Square Platform LLC

Reference29 articles.

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2. Di Luzio R, Dusi R, Mazzotti A, Petroni ML, Marchesini G, Bianchi G. Stress hyperglycemia and complications following traumatic injuries in individuals with/without diabetes: The case of orthopedic surgery. Diabetes, Metab Syndr Obes Targets Ther. 2020;13:9–17.

3. Rose A, Madden AR. Perioperative Glucose Management in Orthopedic Surgery.

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5. CDC. National Diabetes Statistics Report | Diabetes | CDC [Internet]. National Diabetes Statistics Report Estimates of Diabetes and Its Burden in the United States. 2022. Available from: https://www.cdc.gov/diabetes/data/statistics-report/index.html

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