A facile synthesis of bridged polycyclic compounds consisting of chromeno-oxazocine- quinolin skeletons: Eight-Membered-Ring constructions via tandem dinucleophilic addition of 4- hydroxycoumarin to 1,10-phenanthrolin-1-ium Salts-Reference-Cited by-同舟云学术

A facile synthesis of bridged polycyclic compounds consisting of chromeno-oxazocine- quinolin skeletons: Eight-Membered-Ring constructions via tandem dinucleophilic addition of 4- hydroxycoumarin to 1,10-phenanthrolin-1-ium Salts

Published:2023-10-03 Issue: Volume: Page:
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Author:

Sayahi Mohammad Hosein¹,Habbibi Ahmad²,Moazzam Ali³,Hosseini Samanesadat⁴,Larijani Bagher³,Adib Mehdi²,Bahadorikhalili Saeed⁵,Mahdavi Mohammad³

Affiliation:

1. Payame Noor University

2. University of Tehran

3. Tehran University of Medical Sciences

4. Shahid Beheshti University of Medical Sciences

5. Universitat Rovira I Virgili

Abstract

Abstract A novel and efficient tandem synthesis is described for the preparation of bridged polycyclic compounds consisting of chromeno-oxazocine-quinolin through a reaction between benzyl bromide, 1,10-phenanthroline, and 4-hydroxycoumarin in the presence of K2CO3 without a catalyst in tandem reaction. This one-pot protocol provides these valuable desired compounds under mild conditions with excellent efficiency by using simple available starting materials.

Publisher

Research Square Platform LLC

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