Abstract
Objective: The research aims to analyze the impact of home monitoring on INR control and complications in patients undergoing valve replacement and plastic surgery. It is also the first to assess and predict associated risk factors by using a nomogram graph.
Study Design: A retrospective descriptive study
Place and Duration of Study: Department of Cardiovascular Surgery, The First Affiliated Hospital Zhejiang University of Medicine, from January 2021 to January 2023
Methodology:Conducted at the First Affiliated Hospital of Zhejiang University, the retrospective study
involved 505 patients initially, with 406 completing the follow-up. Data collection included patient
characteristic, medical history, valve replacement details, and INR values.
Results: The study found that self-management of INR testing significantly improved the time in
therapeutic range (TTR), reduced INR variance, and decreased complications. Predictive factors for
postoperative coagulation control included gender, history of atrial fibrillation, preoperative
medication history, valve replacement type, and education level.
Conclusion:With home monitoring of INR, patients can take more control of their coagulation management and decrease the frequency of hospital visits. Treatment compliance and outcomes are enhanced when this method is combined with patient education level. The use of a nomogram helps identify patients with stable coagulation function for clinical trials and allows for early intervention in high-risk patients.