Clinical Value of IOTA LR2 and IOTA LR2 Combined with CEUS in Assessing the Nature of Adnexal Masses

Abstract

Abstract Objective To investigate the preoperative assessment of adnexal tumor benignity and malignancy using the International Ovarian Tumour Analysis (IOTA) logistic regression model 2 (LR2) and LR2 combined with contrast-enhanced ultrasound (CEUS). Clinical application of LR2 and CEUS in the preoperative assessment of adnexal tumors was evaluated. Methods One hundred and ninety-eight adnexal tumors were selected, and their nature was evaluated preoperatively according to IOTA LR2 and LR2 combined with CEUS. Pathological and long-term follow-up results were used as the gold standard for comparison. Results For the diagnostic efficacy of LR2 for identifying the nature of ovarian masses, the AUC was 0.90 (0.85–0.94). For the diagnostic efficacy of LR2 combined with CEUS in identifying the benign and malignant nature of ovarian tumors, the AUC was 0.92 (0.88–0.97). Conclusion The IOTA LR2 model has high sensitivity but low specificity. Its diagnostic specificity can be significantly improved by combining it with CEUS. Therefore, LR2 combined with CEUS has high clinical value and can help ultrasonographers determine the benign or malignant nature of adnexal tumors.