Affiliation:
1. All India Institute of Medical Sciences
2. Post Graduate Institute of Medical Education and Research
3. All India Institute of Medical Sciences, New Delhi
Abstract
Abstract
Objectives: To evaluate the pain intensity during 48 hours post retinopathy of prematurity (ROP) screening.
Design: Prospective cohort study
Settings: Level-III NICU in India
Participants: 83 Neonates undergoing first ROP screening
Main outcome measures: Pain assessment using the premature infant pain profile-revised (PIPP-R) score at baseline and 5minutes, 30minutes, 6-, 24-, and 48-hours post-procedure.
Results: The mean gestation and birth weight was 29.8(2.3) weeks and 1256(344) g respectively. The median (IQR) PIPP-R score at baseline was 0 which significantly increased to 10.5(8,12.5) 5min (immediately) after the procedure. At 30min and 6hours, scores were 7(5,8) and 4.5(3,5.5) respectively. After 24 and 48hours, it decreased to 3(0,5) and 0(0,4.5) respectively. Nearly 59%(95% CI:40%–83%) of neonates had severe pain (PIPP-R score>12).
Conclusion: A majority of neonates experience severe pain immediately after ROP screening and mild-moderate pain continues for 6 hours, hence an additional pharmacological agent should be considered for reducing neonatal pain.
Publisher
Research Square Platform LLC
Reference21 articles.
1. Cost-effectiveness of screening and cryotherapy for threshold retinopathy of prematurity;Javitt J;Pediatrics,1993
2. Preterm-associated visual impairment and estimates of retinopathy of prematurity at regional and global levels for 2010;Blencowe H;Pediatr Res,2013
3. Revised_ROP_Guidelines-Web_Optimized.pdf Available from: https://nhm.gov.in/images/pdf/programmes/RBSK/Resource_Documents/Revised_ROP_Guidelines-Web_Optimized.pdf
4. Silverman W. Retrolental Fibroplasia: A Modern Parable. New york: Grune & Stratton; 1980. Chapter 5, The Eye and Oxygen
5. Diode laser for retinopathy of prematurity–early outcome;Goggin M;Br J Ophthalmol,1993