Exploring the link between Diabetes duration and cardiovascular disease in Diabetic patients

Author:

Poochanasri Methavee1,Kookanok Chutawat1,Rangsin Ram2,Kaewput Wisit2,Mungthin Mathirut3,Samakkarnthai Parinya4

Affiliation:

1. Phramongkutklao College of Medicine

2. Department of Military and Community Medicine, Phramongkutklao College of Medicine

3. Department of Parasitology, Phramongkutklao College of Medicine

4. Division of Endocrinology, Department of Medicine, Phramongkutklao College of Medicine

Abstract

Abstract

Background Type 2 Diabetes mellitus (T2DM) significantly impacts cardiovascular disease (CVD). This study investigates the role of diabetes duration in determining CVDs, including coronary artery disease (CAD), congestive heart failure (CHF), cerebrovascular disease (CVA), and peripheral arterial disease (PAD) in Asian individuals with T2DM, based on 2018 data from Thai adults. Methods Thai adult patients with T2DM were recruited, and the duration of diabetes was stratified. Logistic regression analysis was used to identify CVD risk factors, and the final model was performed using multivariable logistic regression analysis. Result The study comprised 34,131 participants. The final model revealed adjusted odds ratios for CAD (AOR 1.80, 95% CI: 1.38–2.34), CHF (AOR 1.81, 95% CI: 1.22–2.67), and PAD (AOR 6.47, 95% CI: 3.09–13.58) with diabetes durations exceeding 15 years. However, the association between diabetes duration and CVA showed less consistency. Conclusion The duration of DM is a significant determinant of cardiovascular risk, especially for conditions including CAD, CHF, and PAD, but not CVA.

Publisher

Research Square Platform LLC

Reference32 articles.

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3. IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045;Cho NH;Diabetes Res Clin Pract,2018

4. Gan, Delice., International Diabetes Federation. & World Diabetes Foundation. Diabetes Atlas. (International Diabetes Federation, 2003).

5. Diabetes and cardiovascular disease: Epidemiology, biological mechanisms, treatment recommendations and future research;Leon BM;World J Diabetes,2015

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