Abstract
Aims
This prospective case series investigated the efficacy of ribose-crosslinked collagen (RCLC) matrices functionalized by crosslinked hyaluronic acid (xHya) for reconstructive treatment of class I and III (b-c) peri-implantitis lesions in a transmucosal healing mode.
Materials and Methods:
Thirteen patients presenting with 15 implants were included. Upon flap reflection, the implants were thoroughly decontaminated employing glycine powder air polishing and adjunctive sodium hypochlorite. For defect augmentation, xHyA was administered to the bony defect walls, exposed implant surfaces, and the RCLC matrix before defect grafting. The full-thickness flap was readapted and sutured around the implant neck for transmucosal healing. Baseline and respective values at the 12 months post-op evaluation were recorded for the clinical parameters peri-implant probing depth (PPD) and bleeding on probing (BoP). Furthermore, two independent investigators analyzed radiographic changes in the defect area.
Results:
The initial mean PPD was 7.2±1.9 mm, and BoP was present in 63% of sites. After 12 months, PPD at the latest visit was 3.2±0.66 mm, which amounted to a respective 3.9±1.85mmreduction, while the BoP frequency dropped to 10% at all sites. Radiographic bone fill was accomplished for 62.8 % of the former defect area, accompanied by a mean MBL gain of 1.02mm around the treated implants.
Conclusions:
Within the limits of this case series, we conclude that the proposed treatment sequence substantially improved peri-implant defects and offered a simplified but predictive technique.