Health-related quality of life and its predictive factors in patients with systemic lupus erythematosus in southwest Iran: a cross-sectional study

Abstract

Abstract Background Quality of life (QoL) is an important measure in health assessment. It is impacted by several factors in Systemic Lupus Erythematosus (SLE) patients which are not entirely clear. This aims of study was evaluation of factors affecting QoL in SLE patients.Methods This cross-sectional study was performed on 140 Iranian SLE patients of Hafiz Hospital. Questionnaire Lupus Quality of Life (LupusQoL) was used to evaluate the quality of life. The patients were evaluated with this questionnaire during 4 weeks in eight dimensions of health, emotional health, body image, pain, planning, intimate relationships and the burden of others. Predictive factors of LupusQoL were evaluated using multivariate linear regression.Results The total mean QoL Score was 65.5 ± 22.4.The highest score of SLE patients' quality of life is related to planning 78.36 ± 25.03 and the lowest score of QoL was related to emotional 54.70 ± 30.51.The results of multivariate analysis showed that duration of disease (β:-1.14, 95% CI:-1.6,-0.61, P:0.001), physical activity(β:-13.2, 95% CI:-20.8,-5.4, P:0.001), kidney involvement (β:-10.38, 95% CI:-17.61,-3.15, P:0.03) and skin involvement(β:-9.5, 95% CI:-18.1,-0.77, P:0.023) were significantly related to the total mean QOL score of SLE patients.Conclusion The findings confirmed that the SLE patients enjoy the middle QoL which can be due to the various factors of disease activity, different bodily systems involvement, and local, cultural, national, and racial aspects.