Isolation of Vagococcus fluvialis from the Bile of a Patient with Chronic Cholecystitis: A Case Report

Abstract

Abstract Background Vagococcus fluvialis is a rare Gram-positive bacterium that is mainly found in animals or animal products, with only a few cases reported in humans. However, it has been implicated in human infections, particularly Vagococcus fluvialis. In this study, the researchers isolated Vagococcus fluvialis from bile samples of a patient with chronic cholecystitis. This is the first report of Vagococcus fluvialis isolation from bile in the literature. To provide valuable clinical information, the researchers performed comprehensive identification and drug susceptibility testing using various methods.Case Presentation The article presents the case of a 66-year-old female who had previously undergone subtotal gastrectomy for diffuse large B-cell lymphoma and was admitted with complaints of abdominal pain. Laboratory tests showed the presence of chronic cholecystitis. Bile samples were cultured and identified as Vagococcus fluvialis using biochemical and mass spectrometry methods, with a 16S rRNA homology of 99.66% with Vagococcus fluvialis in GenBank. The bacteria were found to be sensitive to most antimicrobial drugs, except for clindamycin, erythromycin, and tetracycline. Drug sensitivity testing using the disk diffusion and micro-broth dilution methods provided valuable clinical information for treatment.Conclusion Vagococcus fluvialis, a motile bacterium that can cause human infections, was isolated from the bile of a patient with chronic cholecystitis. Drug sensitivity testing showed most antimicrobial drugs are effective against it except for clindamycin, erythromyin, and tetracycline. This study provides valuable clinical information, but further research is needed on its pathogenicity, epidemiology, and clinical significance.