Investigation of turbulent flow field in maglev centrifugal blood pumps of CH-VAD and Heartmate III using large-eddy simulation

Author:

Wu Peng1,Xiang Wen-Jing2,Zhang Ke-Jia2,Du Guan-Ting2

Affiliation:

1. Southeast University

2. Soochow University

Abstract

Abstract Maglev bearings can avoid serious blood damage caused by mechanical bearings, and has become the primary trend of blood pumps. Maglev blood pumps allow a relatively large clearance to improve blood washout and reduce the stress inside the clearance so that blood damage can be reduced. Nonetheless, large clearances also lead to high secondary flow and turbulence intensity, causing further blood damage. This study aims to conduct a thorough analysis of flow fields in two typical maglev blood pumps, the CH-VAD and Heartmate III which feature distinct designs of secondary flow path and impeller (semi-open versus closed impeller) using large eddy simulation (LES) with a focus on the secondary flows and their interaction with the main flows. LES was found to be superior to the Reynolds-averaged Navier-Stokes (RANS) method in predicting performance curves. At high flow rate (8L/min), the efficiency of CH-VAD remains high compared with 5 L/min, while the efficiency of Heartmate III drops considerably. The wide clearance in Heartmate III induced high secondary flow and flow loss, leading to an large incidence angle at both working conditions. The high viscous stress inside the clearances is the major cause of flow loss and potential blood damage in CH-VAD. This study shows that Maglev bearings dose not guarantee good blood compatibility, clearances should be designed based on trade-offs among high shear stress inside smaller clearance, and strong recirculations caused by larger clearances. This study provides useful reference for the design and optimization of maglev blood pumps.

Publisher

Research Square Platform LLC

Reference36 articles.

1. Hemocompatibility and hemodynamic comparison of two centrifugal LVADs: HVAD and HeartMate3, Biomech;Gil A;Model Mechanobiol,2023

2. Numerical Analysis of Blood Damage Potential of the HeartMate II and HeartWare HVAD Rotary Blood Pumps: Blood Damage Potential of Blood Pumps, Artif;Thamsen B;Organs,2015

3. Assessment of the flow field in the HeartMate 3 using three-dimensional particle tracking velocimetry and comparison to computational fluid dynamics;Thamsen B;ASAIO J,2020

4. Blum C, Landoll M, Strassmann S, Karagiannidis C, Steinseifer U, Neidlin M (2023) Hemolytic Performance Of Extracorporeal Blood Pumps Using Computational Models And Patient Cohort Data, in 49th ESAO Congress, Bergamo, Italy

5. Coporation T (2020) HeartMate 3 Left Ventricular Assist System Instructions for Use

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3