Abstract
The rapid development of fluorescence probe technology has promoted in-depth research in fields such as environment and life medicine. Traditional single channel fluorescent probes can achieve highly sensitive detection of targets, but they appear powerless in complex environments. In addition, in today's deteriorating resource environment, implementing multi-target detection with one probe can effectively save preparation resources, which is in line with the development direction of fluorescent probes. To achieve this goal, designing and preparing multi-site probes is undoubtedly the first choice, but its complex preparation process is daunting. Herein, a novel functional Metal Organic Framework (MOF) was obtained through post modification used UiO-66 was selected as basic skeleton. The novel MOF showed ultra sensitive detection effect on copper ions through coordination. Further, the MOF-Cu2+ can be used to detect the three types of amino acids (cysteine, homocysteine, glutathione) based on the special response between copper and sulfur. Finally, the detection application of probes for Cu2+ in the environment and amino acids in biological systems were researched respectively and achieved good results.