Study of the causes of high pulmonary arterial pressure at Damascus Hospital

Author:

saffaf Sedra1,Romelley Lilas Al Arnaoot2,Almardine Heba3

Affiliation:

1. Faculty of Medicine; Syrian private university (SPU), Damascus, Syria

2. aculty of Medicine; Syrian private university (SPU), Damascus, Syria

3. Faculty of Medicine; Damascus university, Damascus, Syria

Abstract

Abstract

Introduction Pulmonary hypertension refers to high blood pressure in the pulmonary arteries that carry oxygen-poor blood from the heart to the lungs with a mean pulmonary artery pressure of ≥ 25 mm Hg. Materials and methods A descriptive study was conducted on a sample of 246 patients attending Damascus Hospital. Their pulmonary pressure was measured, and several axes related to high pulmonary pressure were studied, including general medical antecedents and then studying the final diagnosis of the cause. A descriptive study of the sample was conducted and then an analytical study that served the research objectives. Results A sample size of 248 patients was collected from the patients attending Damascus Hospital, of which the percentage of males was 51.6%, while the percentage of females was 48.4%. The age of the largest percentage of the sample, about 54.9%, was in the category (61 to 90 years). The percentage of smokers in the sample was 46.7%, about 2.8% of the sample, recorded that they were alcoholic. The majority of the sample recorded that they suffer from several conditions together, at a rate of 65.6%, about 70.3%, recorded no history of surgery. 75.2% of the sample recorded that they suffer from heart disorders, While 15.9% of the sample had disorders and problems in the respiratory system. The vast majority of the sample, 90.2%, had an elevated pulmonary pressure of more than 25 mmHg. the most common cause (final diagnosis) was heart failure, 35.3% . Conclusion • Women were found to be at risk of having high pulmonary pressure with a risk factor of 1.5% more than men • While the results of the one-way analysis of variance test showed that there is a significant effect and an important correlation between the patient’s age and high pulmonary pressure, as the risk increases with a risk factor of 0.43% as age increases. • There is an important correlation and significant effect of smoking on the degree of pulmonary hypertension. • There is an important correlation and significant effect of alcohol consumption on the degree of pulmonary hypertension. • There is an important, statistically significant correlation to the presence of heart disease in the patient and high pulmonary pressure, as heart patients are at risk of having high pulmonary pressure with a risk factor of 1.12% more than patients without heart disease. • Patients with respiratory problems and disorders are at risk of developing pulmonary hypertension, with a risk factor of 1.36%. • There is an important, significant correlation between taking medications (antidepressants, appetite suppressants) and the degree of pulmonary hypertension. • There is an important correlation between the final diagnosis and the cases reported as causes of pulmonary hypertension.

Publisher

Research Square Platform LLC

Reference22 articles.

1. 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension;Galie N;Eur Heart J,2016

2. A global view of pulmonary hypertension;Hoeper MM;Lancet Respir Med,2016

3. Opitz C, Hoeper MM, Gibbs JSR, Hypertension et al (2016) American Academy of Family Physicians. Pulmonary https://familydoctor.org/condition/pulmonary- hypertension/?adfree = true. Accessed 6/2/2022.

4. Current trends and future perspectives in the treatment of pulmonary hypertension: WHO Group II-V (;Bhogal S;Curr Probl Cardiol,2018

5. European Pulmonary Hypertension Association, Classification, Functional WHO, Class (https://www.phaeurope.org/about-ph/classification-and-who-functional-class/). Accessed 6/2/2022

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